August Week
Seven institutions form an integrated team to fuel scientific and technological innovation.
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August Week
Defining the structural basis of how electron flow is controlled in bifurcating enzymes.
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Careers
Probing how electron flow is directed in multi-subunit protein complexes.
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Science
Elucidating the molecular mechanism of electron bifurcation in coupling endergonic and exergonic reactions in efficient chemical bond formation.
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PROJECT OVERVIEW Download Current Brochure The mission of the BETCy EFRC is to define the molecular mechanisms controlling electron flow in coupling electrochemical potential energy to chemical bond formation. The BETCy EFRC examines the mechanisms of Electron Bifurcation (Combining exergonic and endergonic electron transfer reactions for the efficient coupling of electrochemical potential to chemical bond formation), Nucleotide Driven Electron Transfer (Combining energy stored in chemical bonds with electrochemical potential in electron transfer reactions to efficiently drive difficult chemical bond forming reactions) and Catalytic Bias (Mechanisms for controlling directional catalytic rates in proton coupled electron transfer reactions).
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RESEARCH THRUSTS
  • Electron Bifurcation Electron bifurcation is a newly discovered catalytic process that involves combining exergonic and endergonic electron transfer reactions for the efficient coupling of electrochemical potential to chemical bond formation.
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  • Nucleotide Driven Electron Transfer Combining energy stored in chemical bonds with electrochemical potential in electron transfer reactions to efficiently drive difficult chemical bond forming reactions.

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  • Catalytic Bias Mechanisms for controlling directional catalytic rates in proton-coupled electron transfer reactions. We are examinig the mechanisms by which catalytic redox centers can be tuned ...

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AFFILIATED INSTITUTIONS